- Vulgar term equivalent to "shit", or an unwanted substance or act.
- Example: "Same dren, different planet.", "What is this dren?", and "Oh, great, yeah, we have to put up with this dren again."
- It is possible the word has a different meaning to Hynernians as, Rygel said "what the dren are we waiting for?"
(1.06 "Thank God It's Friday... Again")
- (4.09) Chiana says, "And you drenheads are trying to blame that on us?"
- In 2010 a lead character in the popular science-horror film Splice carried the name "Dren", though it was explicitly explained to be "Nerd" spelled backwards.